USP Intent to Republish “General Chapter Hazardous Drugs—Handling in Healthcare Settings

The notice below was published on the USP website ( on 10/13/14 and updated 12/01/14:

“In accordance with section 7.05(c) of the 2010–2015 Rules and Procedures of the Council of Experts, this is to provide notice that the Compounding Expert Committee intends to republish General Chapter <800> Hazardous Drugs—Handling in Healthcare Settings in the Pharmacopeial Forum (PF). The General Chapter, which was originally published in PF 40(3) [May–Jun. 2014], provides standards to protect personnel and the environment when handling hazardous drugs.

The Compounding Expert Committee is republishing General Chapter <800> in PF 41(2) [Mar.–Apr. 2015] due to the nature and significance of the comments received on the original PF proposal. The revision clarifies wording and reflects new and revised guidance documents and stakeholder input.
General Chapter <800> is being presented in advance of its publication in PF 41(2) to allow additional time for public review and comment. To ensure that all comments are addressed, please indicate the line number(s) corresponding to your comments and submit to The General Chapter is available with line numbers at the link below. Comments will be accepted until May 31, 2015.

Download the proposed <800> Hazardous Drugs—Handling in Healthcare Settings at

Should you have any questions, please contact Healthcare Quality Standards staff at